Resistance to drugs remain the most serious threats to public health. The emergence of antibiotic resistance is highly correlated with selective pressure resulting from inappropriate and misuse of these drugs. There is a general increase in the number of multi-resistant microorganisms worldwide. Many cancers are also developing multi-resistance to chemotherapy drugs, which is considered as major mechanism in the failure of many chemotherapy used for cancer treatment. In this talk we shed light on the following points:
- Resistance development worldwide versus the rate of antibiotics development (current state of Antibiotic use and resistance in Human and animals around the globe)
- Discovery and design of new antibiotics and Anti-cancers from natural sources
- Biosynthetic pathway of antibiotic and anticancer drugs and the involved enzymatic machinery
- Molecular mechanism of the antibiotics and anti-cancer mode of actions